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CHRC Publications

ACS REGISTRIES

PEER REVIEW LAB PUBLICATIONS | Manuscripts

Elbarouni B, Goodman SG , Yan RT, Casanova A, Al-Hesayen A, Pearce S, Fitchett DF, Langer A, Yan AT, for the Canadian ACS Registries Investigators. Impact of Delayed Presentation on Management and Outcome of Non-ST Elevation Acute Coronary Syndromes. Am Heart J 2008 (in press).

Lim KD, Yan AT, Casanova A, Yan RT, Mendelsohn A, Jolly S, Fitchett DH, Langer A, Goodman SG . Quantitative troponin elevation does not provide incremental prognostic value beyond comprehensive risk stratification in patients with Non-ST segment elevation acute coronary syndromes. Am Heart J. 2008 Apr;155(4):718-24

Vijayaraghavan R, Yan AT, Tan M, Fitchett DH, Georgescu AA, Hassan Q, Langer A, Goodman SG , for the Canadian Acute Coronary Syndromes Registry Investigators. Local Hospital vs. Core-Laboratory Interpretation of the Admission Electrocardiogram in Acute Coronary Syndromes: Increased Mortality in Patients with Unrecognized ST-Elevation Myocardial Infarction. Eur Heart J. 2008 Jan;29(1):31-7.

Yan AT, Yan RT, Tan M, Huynh T, Soghrati K, Brunner LJ, DeYoung P, Fitchett DH, Langer A, Goodman SG , for the Canadian ACS Registries Investigators. Optimal Medical Therapy at Discharge in Patients with Acute Coronary Syndromes: Temporal Changes, Characteristics, and 1-year Outcome. Am Heart J 2007;154:1108-15.

Lee CH, Tan M, Yan AT, Yan RT, Fitchett D, Grima EA, Langer A, Goodman SG , for the Canadian Acute Coronary Syndromes II (ACS II) Registry Investigators. The Utilization of Cardiac Catheterization for Non-ST-Segment Elevation Acute Coronary Syndromes According to Initial Risk: Reasons Why Physicians Choose Not to Refer Their Patients . Arch Intern Med 2008;168(3):291-296.

Segev A, Strauss BH, Tan M, Buller CE, Mendelsohn AA, Langer A, Goodman SG .

Risk factors and outcome of in-hospital ischemic stroke in patients with non-ST elevation acute coronary syndromes. International Journal of Cardiology 2007; (in press).

Zia MI, Goodman SG , Peterson ED, Mulgund J, Chen AY, Langer A, Tan M, Ohman EM, Gibler WB, Pollack Jr CV, Roe MT. Paradoxical Utilization of Invasive Cardiac Procedures for Patients with Non ST-segment Elevation Myocardial Infarction: An International Perspective from the CRUSADE Initiative and Canadian ACS Registries. Can J Cardiol 2007;23:1073-79.

Yan A, Yan R, Tan M, Fung A, Cohen E, Fitchett D, Langer A, Goodman SG . Management Patterns in Relation to Risk Stratification Among Patients with non-ST Elevation Acute Coronary Syndromes. Arch Int Med 2007;167:1009-16.

PEER REVIEW PUBLICATIONS - ACS Registry (I and II) | Manuscripts

Yan RT, Yan AT, Tan M, McGuire DK, Leiter LA, Fitchett DH, Lauzon C, Lai K, Chow CM, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Under-utilization of evidence-based treatment partly explains the worse clinical outcome in diabetic patients with acute coronary syndromes. Am Heart J 2006;152:676-83.

Yan AT, Yan RT, Tan M, Casanova A, Labinaz M, Sridhar K, Fitchett DH, Langer A, Goodman SG . Risk Scores for Risk Stratification in Acute Coronary Syndromes: Useful But Simpler is Not Necessarily Better. Eur Heart J 2007;28(9):1072-78.

Yan AT, Yan RT, Tan M, Chow CM, Fitchett DH, Georgescu A, Hassan Q, Luchansky J, Langer A, Goodman SG . ST-segment depression in non-ST elevation acute

coronary syndromes: Quantitative analysis may not provide incremental prognostic value beyond comprehensive risk stratification. Am Heart J 2006;152(2):270-76.

Segev A, Strauss BH, Tan M, Mendelsohn AA, Lai K, Ashton T, Fitchett D, Grima E, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registries Investigators. Prognostic significance of admission heart failure in patients with non ST-elevation acute coronary syndromes (From the Canadian Acute Coronary Syndrome Registries). Am J Cardiol 2006;98:470-473.

Yan AT, Yan RT, Tan M, Constance C, Lauzon C, Zaltzman J, Wald R, Fitchett D, Langer A, Goodman SG . Treatment and outcome of patients with renal dysfunction across the broad spectrum of acute coronary syndromes. Can J Cardiol 2006;22(2):115-120.

Yan R, Yan AT, Tan M, Chow CM, Fitchett DH, Ervin FL, Cha JYM, Langer A, Goodman SG. Age related differences in the management and outcome of patients with acute coronary syndromes: Insights from the Canadian Acute Coronary Syndrome Registry. Am Heart J 2006;151:352-59.

Yan AT, Yan RT, Mary Tan M, Eagle KA, Granger CB, Dabbous OH, Fitchett D, Grima E, Langer A, and Goodman SG , for the Canadian Acute Coronary Syndromes (ACS) Registry Investigators. In-Hospital Revascularization and One-Year Outcome of Acute Coronary Syndrome Patients Stratified by the GRACE Risk Score. Am J Cardiol 2005;96:913-916.

Jackevicius CA, Alter D, Cox J, Daly P, Goodman S , Filate W, Newman A, Tu JV, for the Canadian Cardiovascular Outcomes Research Team. Acute treatment of myocardial infarction in Canada 1999-2002. Can J Cardiol Vol 2005;21:145-152.

PEER REVIEW PUBLICATIONS - ACS Registry (I and II) | Manuscripts

Segev A, Strauss BH, Tan M, Constance C, Langer A, Goodman SG , for the Canadian Acute Coronary Syndromes Registries Investigators. Predictors and One-Year Outcome of Major Bleeding in Patients with Non-ST Elevation Acute Coronary Syndromes: Insights from the Canadian Acute Coronary Syndrome Registries. Am Heart J 2005;150(4):690-94.

Yan AT, Jong P, Yan RT, Tan M, Fitchett D, Chow CM, Roe MT, Pieper KS, Langer A, Goodman SG , for the Canadian Acute Coronary Syndromes (ACS) Registry Investigators. Clinical trial-derived risk model may not generalize to real-world patients with acute coronary syndrome . Am Heart J 2004;148:1020-27.

Yan AT, Yan RT, Tan M, Chow CM, Fitchett D, Stanton E, Langer A, Goodman SG , for the Canadian Acute Coronary Syndromes (ACS) Registry Investigators. Troponin is more useful than creatine kinase in predicting one-year mortality among acute coronary syndrome patients. Eur Heart J 2004;25:2006-2012.

Yan AT,Tan M, Fitchett D, Chow CM, Fowlis RA, McAvinue TG, Roe MT, Peterson ED, Tu JV, Langer A, Goodman SG , for the Canadian Acute Coronary Syndromes Registry Investigators. One-Year Outcome of Patients After Acute Coronary Syndromes (from the Canadian Acute Coronary Syndromes Registry). Am J Cardiol 2004;94:25-29.

PEER REVIEW PUBLICATIONS - ACS Registry (I and II) | Abstracts

Bagnall AJ, Goodman SG , Huynh T, Cheema AN, Fitchett DH, Yan RT, Langer A, Yan AT, for the Canadian ACS Registry I and II Investigators. Temporal Changes in the Use of Early Invasive Management for Non-ST Elevation Acute Coronary Syndromes: Influence of Age on Treatment Selection and Outcome. J Am Coll Cardiol 2008;51(Suppl A):A216.

Huynh T, Yan A, Kouz S, Rinfret S, Schampaert E, Eisenberg MJ, Lauzon C, Afilalo M, Goodman S . A new risk score (C-AMI) for the early stratification of patients with ST-segment Elevation Myocardial Infarction. Circulation 2007;116(Suppl 2):II-317.

Yan AT, Yan RG, Tan M, Sridhar K, Labinaz M, Cohen EA, Fitchett DH, Langer A, Goodman SG . Comparison of the TIMI and GRACE Risk scores in the Canadian Acute Coronary Syndromes II Registry: simpler is not necessarily better. J Am Coll Cardiol 2006;47(Suppl A):224A.

Yan RT, Yan AT, Allegrone J, Lopez-Sendon J, Granger C, Gore J, Budaj A, Georgescu A, Hassan Q, Goodman SG . Failure To Identify St-Segment Deviation Or Left Bundle Branch Block On The Presenting Electrocardiograms In Patients With Acute Coronary Syndromes Is Related To More Adverse Clinical Outcome. Can J Cardiol 2006; 22(Suppl D):194D.

RT Yan RT, Yan AT, Allegrone J, Kennelly B, Budaj A, Georgescu A, Hassan Q, Goodman SG . ST-segment Depression in Non-ST Elevation Acute Coronary Syndromes: Quantitative Analysis Does Not Provide Incremental Prognostic Value Beyond Comprehensive Risk Stratification. Can J Cardiol 2006; 22(Suppl D):190D.

Lee C, Yan AT, Yan RT, Tan M, Grima E, De Young JP, Fitchett D, Langer A, Goodman SG . The Use of Anti-platelets and Anti-thrombotics in Non-ST Elevation Acute Coronary Syndromes - The Reasons Physicians choose Not to Prescribe. Can J Cardiol 2006; 22(Suppl D):192D.

Yan AT, Yan RT, Tan M, Lee C, Fitchett D, Langer A, Goodman SG . The Association Between On-Site Availability and Use of Cardiac Catheterization Facilities in the Contemporary Management of Non-St Elevation Acute Coronary Syndromes. Can J Cardiol 2006; 22(Suppl D):194D.

Yan RT, Yan AT, Tan M, Baer C, Leiter LA, Chow CM, Fitchett DH, Langer A, Goodman SG . Underutilization of an Invasive Management Strategy in Canadian Diabetic Patients with Non-ST Elevation Acute Coronary Syndromes: The Problem Still Remains. Circulation 2005;112(Suppl):II-694.

Yan AT, Yan RT, Tan M, Sridhar K, Labinaz M, Cohen EA, Fitchett DH, Langer A, Goodman SG . Comparison of the TIMI and GRACE Risk Scores in the Canadian Acute Coronary Syndromes II Registry: Simpler isn't Necessarily Better. Can J Cardiol 2005;21(Suppl C):218C.

Yan AT, Yan RT, Tan M, Ma PT, Lim KD, Chow CM, Fitchett DH, Langer A, Goodman SG . Greater Use of Evidence-Based Medical Therapies in Non-ST Elevation Acute Coronary Syndromes Over Time: Insights from the Canadian ACS Registries. Can J Cardiol 2005;21(Suppl C):162C.

Yan AT, Yan RT, Tan M, Fung AY, Chow CM, Cantor WJ, Cohen EA, Fitchett DH, Langer A, Goodman SG , for the Canadian ACS Registry Investigators. Despite the Temporal Increases, Coronary Angiography and Revascularization Remains Paradoxically Directed Towards Low Risk Non-ST Elevation Acute Coronary Syndrome Patients in Canada. JACC 2005;45(Suppl A):190A.

Yan RT, Yan AT, Tan M, Oh M, Zaltzman JS, Wald R, Fitchett DH, Langer A, Goodman SG . Evidence-based therapies for acute coronary syndromes are equally effective but underutilized among patients with renal dysfunction. Circulation 2004;110(Suppl III):III-576.

Segev A, Strauss BH, Tan M, Constance C, Langer A, Goodman SG. Predictors and long-term outcome of major bleeding in patients with non-ST-elevation acute coronary syndromes: insgiths from the Canadian Acute Coronary Syndrome Registries. Circulation 2004;110(Suppl III):III-574.

Chow CM, Tan M, Fitchett DH, Langer A, Goodman SG , Rudski L, for the Canadian ACS Registry Investigators. Outcomes of Early vs. Late Coronary Artery Bypass Graft post-acute myocardial infarction: Insights from the Canadian Acute Coronary Syndrome Registry. Can J Cardiol 2004;20(Suppl D):170D.

Yan AT, Yan RT, Tan M, Georgescu AA, Hassan Q, Luchansky J, Chow CM, Fitchett DH, Langer A, Goodman SG , for the Canadian ACS Registry Investigators. ST Segment Depression is an Independent Predictor of One-year Mortality in Non-ST Elevation Acute Coronary Syndromes But Quantitative ST-segment Analysis Does Not Provide Incremental Predictive Value Beyond Comprehensive Risk Stratification. Can J Cardiol 2004;20(Suppl D):124D.

Yan RT, Yan AT, Tan M, Oh M, Zaltzman J, Wald R, Fitchett DH, Langer A, Goodman SG , for the Canadian ACS Registry Investigators. Evidence-based Therapies For Acute Coronary Syndromes Are Equally Effective But Underutilized Among Patients with Renal Dysfunction. Can J Cardiol 2004;20(Suppl D):122D.

Yan AT, Jong P, Yan R, Tan M, Kuritzky RA, Drozdiak L, Chow CM, Fitchett DH, Langer A, Goodman SG . Risk scores derived from clinical trials do not generalize to real world acute coronary syndrome patients: insights from the Canadian Acute Coronary Syndromes Registery. J Am Coll Cardiol 2004;43(5;Suppl A):262A.

Yan R, Yan AT, Tan M, Leiter L, Chow CM, Fitchett DH, Fowlis R, Janzen I, Langer A, Goodman SG . Diabetic patients with acute coronary syndromes were undertreated and had worse one-year outcome. J Am Coll Cardiol 2004;43(5;Suppl A):248A.

Yan R, Yan AT, Tan M, Chow CM, Fitchett DH, Ervin FL, Martin H, Cha JY, Langer A, Goodman SG . Elderly acute coronary syndrome patients were undertreated with worse one-year outcome: findings from a contemporary registry. J Am Coll Cardiol 2004;43(5;Suppl A):183A.

Zia M, Goodman SG , Row MT, Mulgand J, Langer A, Tan M, Ohman EM, Gibler WB, Pollack CV, Peterson ED. Paradoxical utilization of invasive cardiac procedures for patients with non-ST segment elevation myocardial infarction: an American-Canadian comparison from the CRUSADE initiative and Canadian registries. J Am Coll Cardiol 2004;43(5;Suppl A):276A.

Yan R, Yan AT, Tan M, Chow CM, Fitchett DH, Zaltzman JS, Pearce S, Langer A, Goodman SG . Renal dysfunction in patients with acute coronary syndromes is associated with worse mortality and myocardial infarction at one year follow-up. Circulation 2003;108(suppl):IV-314.

PEER REVIEW PUBLICATIONS - ACS Registry (I and II) | Abstracts

Yan AT, Yan R, Tan M, Stanton E, Lawrence M, Chow CM, Fitchett DH, Langer A, Goodman SG . Troponin status is more useful than creatine kinase in predicting one-year mortality in acute coronary syndrome patients. Circulation 2003;108(suppl):IV-313.

Chow CM, Yan AT, Yan R, Tan M, Adams GS, Lahey K, Fitchett DH, Langer A, Goodman SG . Admission and follow-up ECG classifications of acute coronary syndromes: a tale of tow systems (ST versus Q wave status). Circulation 2003;108(suppl):IV-383-384.

Vijayaraghavan R, Tan M, Fitchett DH, Georgescu AA, Hassan Q, Luchansky J, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Canadian Hospital vs. Core-Laboratory Interpretation of the Admission ECG in Acute Coronary Syndromes: The Impact of Disagreement on Treatments and Outcomes .Can J Cardiol 2003;19(suppl A):124A.

Chow CM, Tan M, Abramson BL, De Young JP, Watt M, Burrows M, Fitchett DH, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Gender Differences in Acute Myocardial Infarction (MI): Contemporary Canadian Practice and Outcomes. Can J Cardiol 2003;19(suppl A):257A.

Yan AT, Yan R, Tan M, Stanton E, Lawrence M, Chow CM, Fitchett DH, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Troponin Status Is More Useful Than Creatinine Kinase In Predicting One-year Mortality in Canadian Acute Coronary Syndrome Patients. Can J Cardiol 2003;19(suppl A):248A.

Chow CM, Yan AT, Yan R, Tan M, Adams GS, Lahey K, Fitchett DH, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Admission and Follow-Up ECG Classifications of Acute Coronary Syndromes: A Tale of Two Systems (ST versus Q Wave Status). Can J Cardiol 2003;19(suppl A):125A.

Yan R, Yan AT, Tan M, Chow CM, Fitchett DH, Ervin FL, Martin H, Cha JYM, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Age-related Differences In Clinical Characteristics, Management And One-year Outcome Of Patients With Acute Coronary Syndrome: Insights From The Canadian Acute Coronary Syndromes Registry. Can J Cardiol 2003;19(suppl A):256A.

Yan R, Yan AT, Tan M, Chow CM, Zaltzman JS, Pearce S, Fitchett DH, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Renal Dysfunction In Patients With Acute Coronary Syndromes Is Associated With Higher Risks of Death and Myocardial Infarction At One-year Follow-up. Can J Cardiol 2003;19(suppl A):260A.

PEER REVIEW PUBLICATIONS - ACS Registry (I and II) | Abstracts

Yan AT, Yan R, Tan M, Fitchett D, Chow DM, Hui W, Kvill L, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Underutilization of Key Secondary Prevention Therapies One Year Following an Acute Coronary Syndrome in Canada. Can J Cardiol 2003;19(suppl A):207A.

Yan R, Yan AT, Tan M, Fitchett DH, Chow CM, Abramson BL, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Lifestyle Modification and Cardiac Rehabilitation Following Acute Coronary Syndromes in Canada: One-year Results from the Lifestyle Substudy of the Canadian ACS Registry. Can J Cardiol 2003;19(suppl A):258A.

Yan AY, Jong P, Yan R, Tan M, Kuritzky RA, Drozkiak L, Chow CM, Fitchett D, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Risk Scores Derived From Clinical Trials Do Not Apply To ""Real World"" Canadian Acute Coronary Syndrome . Can J Cardiol 2003;19(suppl A):256A.

Yan R, Yan AT, Chow CM, Leiter LA, Tan M, Fowlis R, Janzen I, Fitchett DH, Langer A, Goodman SG , for the Canadian Acute Coronary Syndrome Registry Investigators. Diabetic Patients With Acute Coronary Syndromes Were Under-treated And Had Worse One-year Mortality. C an J Cardiol 2003;19(suppl A):256A.

Yan R, Tan M, Langer A, Goodman S. Lifestyle modification and cardiac rehabilitation following acute coronary syndrome in Canada - one-year results from the life-style substudy of the Canadian Acute Coronary Syndromes Registry. Clin Invest Med 2003;26:89.

Yan R, Yan A, Tan M, Langer A, Goodman S. Adherence to secondary prevention therapies following acute coronary syndrome: one-year results from the Canadian Acute Coronary Syndromes Registry. Clin Invest Med 2003;26:91.

Yan AT, Goodman SG, Tan M, Fitchett D, Chow C-M, Langer A for the Canadian ACS Registry Investigators. Adherence to secondary prevention therapies following acute coronary syndromes: one-year results from the Canadian Acute Coronary Syndrome Registry. J Am Coll Cardiol 2003;41(suppl A):382A

Yan A, Goodman SG , Tan M, Fitchett D, Chow CM, Lai K, Langer A, for the Canadian ACS Registry Investigators. Management and outcomes of patients with acute coronary syndromes: one year results from the Canadian Acute Coronary Syndrome Registry. JACC 2003 (in press). J Am Coll Cardiol 2003;41(suppl A):349A

PEER REVIEW PUBLICATIONS - ACS Registry (I and II) | Abstracts

Chow CM, Goodman SG , Tan M, Greening-Aitken C, Witt I (deceased), Chisholm P, Ashton T, Arsenault B, Gupta S, Langer A. Regional differences in the outcomes, risk factors and demographics among patients with acute myocardial infarction: insights from the Canadian ACS Registry. Can J Cardiol 2002;18(suppl B):142B.

Yan A, Goodman SG , Tan M, Greening-Aitken C, Chow CM, Fitchett D, Lai K, Johnston D, Stensland J, Brossoit R, Robert C, Langer A. Management and outcomes of patients following acute coronary syndromes (ACS): one year follow-up from the Canadian ACS Registry. Can J Cardiol 2002;18(suppl B):152B.

Goodman SG , Fitchett D, Tan M, Spindler C, Timothee JR, Racicot D, Cloutier L, McAvinue T, Dorion D, Langer A, for the Canadian Acute Coronary Syndromes Registry Group, Toronto, Greenfield Park, and Miramichi. Management of acute coronary syndromes (ACS) in Canada: anti-platelet/thrombotic therapy in the first 24 hours. Can J Cardiol 2001;17(suppl C):228C.

Goodman SG , Tan M, Spindler C, Tremblay B, Darveau C, Lauzon C, Ouimet F, Langer A, for the Canadian Acute Coronary Syndromes Registry Group, Toronto, Quebec City and Thetford Mines. Secondary prevention following acute coronary syndromes in Canada: an evidence-based approach? Can J Cardiol 2001;17(suppl C):166C-167C.

Goodman SG, Tan M, Spindler C, Walker M, Churchill C, Skarpinsky B, Constance C, Maltais M, Langer A, for the Canadian Acute Coronary Syndromes Registry Group, Toronto, Prince Albert, and Montreal. Coronary angiography and revascularization in acute coronary syndromes (ACS): What the Canadian ACS Registry reveals about "real world" management during index hospitalization. Can J Cardiol 2001;17(suppl C):228C.

ECG CORE LAB

PEER REVIEW PUBLICATIONS | Manuscripts

Armstrong PW, McDonald M, Fu Y, Zeymer U, Wagner G, Goodman SG , Ross A, Granger CB, Van de Werf C. Adverse outcomes in fibrinolytic-based facilitated PCI: Insights from the ASSENT-4 PCI Electrocardiographic Substudy. Eur Heart J 2008 (in press).

Yan RT, Yan AT, Granger CB, Lopez-Sendon J, Brieger D, Kennelly B, Budaj A, Steg PG, Georgescu AA, Hassan Q, MD, Goodman SG, on behalf of the Global Registry of Acute Coronary Events (GRACE) Electrocardiogram Substudy Group. Usefulness of Quantitative Versus Qualitative ST-Segment Depression for Risk Stratification of Non-ST Elevation Acute Coronary Syndromes in Contemporary Clinical Practice. Am J Cardiol 2008;101:919-924.

Vijayaraghavan R, Yan AT, Tan M, Fitchett DH, Georgescu AA, Hassan Q, Langer A, Goodman SG , for the Canadian Acute Coronary Syndromes Registry Investigators. Local Hospital vs. Core-Laboratory Interpretation of the Admission Electrocardiogram in Acute Coronary Syndromes: Increased Mortality in Patients with Unrecognized ST-Elevation Myocardial Infarction. Eur Heart J 2008;29:31-7.

Toma M, Fu Y, Wagner GS, Goodman SG , Granger CB, Wallentin L, Van de Werf F, Armstrong PW. Risk stratification in ST elevation myocardial infarction is enhanced by combining baseline ST deviation and subsequent ST segment resolution. Heart 2008; 94;e6.

Yan RT, Yan AT, Allegrone J, Lopez-Sendon J, Granger CB, Gore JM, Budaj A, Georgescu AA, Hassan Q, Luchansky J, Van de Werf F, Goodman SG . Differences Between Local Hospital and Core Laboratory Interpretation of the Admission Electrocardiogram in Patients With Acute Coronary Syndromes are Associated with Worse Outcome. Am J Cardiol 2007; 100;169-174.

Goodman SG , Fu Y, Langer A, Barr A, Tan M, Wagner GS, Barbagelata A, Sgarbossa EB, Birnbaum Y, Granger CB, Califf RM, Van de Werf F, Topol EJ, Armstrong PW, for the GUSTO-IIb Investigators. The prognostic value of the admission and pre-discharge electrocardiogram in acute coronary syndromes: the GUSTO-IIb ECG Core Laboratory experience. Am Heart J 2006;152(2):277-84.

Yan AT, Yan RT, Tan M, Chow CM, Fitchett DH, Georgescu A, Hassan Q, Luchansky J, Langer A, Goodman SG . ST-segment depression in non-ST elevation acute

coronary syndromes: Quantitative analysis may not provide incremental prognostic value beyond comprehensive risk stratification. Am Heart J 2006;152(2):270-76.

PEER REVIEW PUBLICATIONS | Manuscripts (cont'd)

Al-Faleh H, Fu Y, Wagner G, Goodman S , Sgarbossa E, Granger C, Van de Werf F, Wallentin L, Armstrong PW. Unraveling the spectrum of left bundle branch block in acute myocardial infarction: Insights from the Assessment of the Safety and Efficacy of a New Thrombolytic (ASSENT 2 and 3) trials. Am Heart J 2006;151:10-15.

Petrina M, Goodman SG , Eagle K. The Twelve-Lead Electrocardiogram as a Predictive Tool of Mortality after Acute Myocardial Infarction - Current Status in an Era of Revascularization and Reperfusion. Am Heart J 2006;152(1):11-8.

Goodman SG , Bozovich GE, Tan M, Dos Santos A, Gurfinkel EP, Cohen M, Langer A, for the Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group (ESSENCE) Study Group . The greatest benefit of enoxaparin over unfractionated heparin in acute coronary syndromes is achieved in patients presenting with ST segment changes: The ESSENCE ECG Core Laboratory Substudy. Am Heart J 2006;151:791-797.

Georgescu A, Fu Y, Yau C, Hassan Q, Luchansky J, Armstrong PW, Wagner G, Van de Werf F, Goodman SG , for the Assessment of the Safety and Efficacy of a new Thrombolytic Regimen Trial (ASSENT-3) Investigators. Short and Long Term Outcomes of Patients with Electrocardiographic Left Ventricular Hypertrophy After Fibrinolysis for Acute Myocardial Infarction. American J Cardiol 2005;92:1050-1052.

Johanson P, Armstrong PW, Barbagelata NA, Chaitman BR, Clemmensen P, Dellborg M, French J, Goodman SG , Green CL, Krucoff MW, Langer A, Pahlm

O, Reilly P, Wagner GS. An academic ECG Core Lab perspective of the FDA initiative for digital ECG capture and data management in large-scale clinical trials. Drug Information Journal 2005;39:345-351.

Alexander JH, Yang H, Becker RC, Kodama K, Goodman S, Dyke CK, Kleiman NS, Hochman JS, Berger PB, Cohen EA, Lincoff AM, Burton JR, Bovill EG, Kawai C, Armstrong PW Harrington RA, on behalf of the XaNADU-ACS Investigators. First experience with direct, selective factor Xa inhibition in patients with non-ST-elevation acute coronary syndromes: Results of the XaNADU-ACS Trial. Journal of Thrombosis Haemostasis 2005;3:439-447.

Taher T, Fu Y, Wagner GS, Goodman SG , Fresco C, Granger CB, Wallentin L, Van de Werf F, Verheugt F, Armstrong PW. Aborted Myocardial Infarction in Patients With ST-Segment Elevation Insights From the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen-3 Trial Electrocardiographic Substudy. J Am Coll Cardiol 2004;44:38-43.

PEER REVIEW PUBLICATIONS | Manuscripts (cont'd)

Johanson P, Fu Y, Goodman SG , Dellborg M, Armstrong PW, Krucoff MW, Wallentin L, Wagner GS. A dynamic model forecasting myocardial infarct size before, during and after reperfusion therapy - An ASSENT-2 ECG/VCG substudy. Eur Heart J 2005;26:1726-33.

Barbagelata A, Di Carli MF, Califf RM, Garg J, Birnbaum Y, Grinfield L, Gibbons RJ, Granger CB, Goodman SG , Wagner GS, Majaffey KW. Electrocardiographic infarct size assessment after thrombolysis: Insights from the acute myocardial infarction Study Adenosine (AMISTAD) trial. Am Heart J 2005;150;659-665.

Kaul P, Newby LK, Fu Y, Mark DB, Goodman SG , Wagner GS, Harrington RA, Granger CB, Van de Werf F, Ohman EM, Armstrong, for the VIGOUR Group. The Relationship between Baseline Risk and Treatment Decisions in Non-ST Elevation Acute Coronary Syndromes: An Examination of International Practice Patterns. Heart (in press).

Armstrong PW, Wagner B, Goodman SG , Van de Werf F, Granger G, Wallentin L, Fu Y, for the ASSENT 3 Investigators. ST segment resolution in ASSENT 3: insights into the role of three different treatment strategies for acute myocardial infarction. Eur Heart J 2003;24:1515-22

Lockwood E, Fu Y, Wing B, Van de Werf F, Granger CB, Armstrong PW, Goodman SG for the ASSENT-2 Investigators. Does 24-hour ST-segment resolution postfibrinolysis add prognostic value to a Q wave? An ASSENT 2 electrocardiographic substudy. Am Heart J 2003;146:640-5.

Tjandrawidjaja MC, Fu Y, Goodman SG , Van de Werf F, Granger CB,Armstrong PW. The impact of gender on the treatment and outcomes of patients with early reinfarction after fibrinolysis: Insights from ASSENT 2. Eur Heart J 2003;24:1024-34.

Goodman SG , Barr A, Langer A, Wagner GS, Fitchett D, Armstrong PW, Naylor CD. Development and prognosis of non-Q wave myocardial infarction in the thrombolytic era. Am Heart J 2002;144:243-50.

Fu Y, Goodman S, Chang W-C, Van de Werf F, Granger CB, Armstrong PW, for the ASSENT-2 Investigators. Time to treatment influences the impact of ST segment resolution on one-year prognosis: insights from ASSENT 2. Circulation 2002;104:2653-59.

PEER REVIEW PUBLICATIONS | Manuscripts (cont'd)

Kaul P, Fu Y, Chang WC, Harrington RA, Wagner GS, Goodman SG , Granger CB, Moliterno DJ, Van de Werf F, Califf RM, Topol EJ, Armstrong PW, for the PARAGON-A and GUSTO-IIb Investigators. Prognostic value of ST segment depression in acute coronary syndromes: insights from PARAGON-A applied to GUSTO-IIb. J Am Coll Cardiol 2001;38:64-71.

Birnbaum Y, Goodman S , Barr A, Gates KB, Barbash GI, Battler A, Barbagelata A, Clemmensen P, Sgarbossa EB, Granger CG, Califf RM, Wagner GS. Comparison of primary coronary angioplasty versus thrombolysis in patients with ST-segment elevation acute myocardial infarction and grade II and grade III myocardial ischemia on the enrollment electrocardiogram. Am J Cardiol 2001;88:842-847.

Anderson S, Pahlm O, Bacharova L, Barbagelata A, Chaitman B, Clemmensen P, Goodman S , Heden B, Klootwijk P, Lauer M, MacFarlane P, Rautaharju P, Reddy S, Selvester R, Sgarbossa E, Underwood D, Warner R, Wagner G. Standards for the function of an academic 12-lead electrocardiographic core laboratory. J Electrocardiol 2001;34:41-47.

Barbash GI, Birnbaum Y, Bogaerts K, Hudson M, Lesaffre E, Fu Y, Goodman SG, Houbracken K, Munsters K, Granger CB, Pieper K, Califf RM, Topol EJ, van de Werf F. Treatment of reinfarction after thrombolytic therapy for acute myocardial infarction: an analysis of outcome and treatment choices in the GUSTO I and ASSENT 2 studies. Circulation 2001;103:954-960.

Sgarbossa EB, Meyer PM, Pinski SL, Pavlovic-Surjancev B, Barbagelata A, Goodman SG , Lum AS, Underwood DA, Gates KB, Califf RM, Topol EJ, Wagner GS. Negative T waves shortly after ST-elevation acute myocardial infarction are a powerful marker for improved survival rate. Am Heart J 2000;140:385-94.

Barbagelata A, Califf RM, Sgarbossa EB, Goodman SG, Knight D, Mark DB, Granger CB, Ohman M, Wagner G. The use of resources, quality of life and clinical outcomes in patients with and without new Q waves after thrombolytic therapy for acute myocardial infarction (from GUSTO-I). Am J Cardiol 2000;86:24-29.

Sgarbossa EB, Pinsky SL, Barbagelata A, Goodman SG, Natale A, Gates KB, Wagner GS. ECG subanalyses in clinical trials: an investigator's perspective. J Electrocardiol 1999;32(suppl):114-121.

Hochrein J, Fucheng S, Pieper KS, Lee KL, Gates K, Armstrong PW, Weaver

WD, Goodman S, Topol EJ, Califf RM, Granger CB, Wagner GS. Higher T-wave amplitude associated with better prognosis in patients receiving thrombolytic therapy for acute myocardial infarction (a GUSTO-I substudy). Am J Cardiol 1998;81:1078-1084.

PEER REVIEW PUBLICATIONS | Manuscripts (cont'd)

Goodman S , Langer A, Ross AM, Wildermann NM, Barbegelata A, Sgarbossa EG, Wagner GS, Granger CB, Califf RM, Topol EJ, Simoons ML, Armstrong PW, for the GUSTO-I Angiographic Investigators. Non-Q versus Q-wave myocardial infarction after thrombolytic therapy: angiographic and prognostic insights from the GUSTO-I angiographic substudy. Circulation 1998;97:444-450.

Sgarbossa EB, Pinski SL, Topol EJ, Califf RM, Barbagelata A, Goodman SG , Gates KB, Granger CB, Miller DP, Underwood DA, Wagner GS, for the GUSTO-I Investigators. Acute myocardial infarction and complete left bundle branch block at hospital admission: clinical characteristics and outcome in the thrombolytic era. J Am Coll Cardiol 1998;31:105-110.

Barbagelata A, Califf RM, Sgarbossa EB, Goodman SG , Stebbins AL, Granger CB, Suarez LD, Borruel M, Gates K, Starr S, Wagner GS. Thrombolysis and Q wave versus non-Q wave first acute myocardial infarction: a GUSTO-I substudy. J Am Coll Cardiol 1997;29:770-777.

Langer A, Goodman SG , Topol EJ, Charlesworth A, Skene AM, Wilcox RG, Armstrong PW for the LATE Study Investigators. Late assessment of thrombolytic efficacy (LATE) study: Prognosis in patients with non-Q wave myocardial infarction. J Am Coll Cardiol 1996;27:1327-1332.

Singh N, Mironov D, Goodman SG , Morgan CD, Langer A. Treatment of silent ischemia in unstable angina: a randomized comparison of sustained-release verapamil versus metoprolol. Clin Cardiol 1995;18:653-658.

Abstracts

McDonald MA, Fu Y, Zeymer U, Wagner GS, Goodman SG , Ross AM, Granger CB, Van de Werf F, Armstrong PW. Adverse Outcomes in Fibrinolytic-Based Facilitated PCI: Insights From the ASSENT-4 PCI electrocardiographic Substudy. Can J Cardiol 2007;23(Suppl C):223C.

PEER REVIEW PUBLICATIONS - ECG Core Laboratory | Abstracts (cont'd)

Petrina M, Eagle KA, Lopez-Sendon J, Step PG, Fox KA, Stiles M, Quill A, Goodman SG , for the GRACE Investigators. The Prognostic Value of the 12-Lead Electrocardiogram (ECG) in Patients Presenting with Acute Coronary Syndromes (ACS): Insights from the Global Registry of Acute Coronary Events (GRACE) ECG Substudy. J Am Coll Cardiol 2007;49(Suppl A):187A.

Yan AT, Yan RT, Allegrone J, Kennelly B, Anderson F, Steg PG, Goodman SG . Prevalence and Prognostic Significance of ST Elevation In aVR in Patients with Non-ST Elevation Acute Coronary Syndromes. Can J Cardiol 2006; 22(Suppl D):193D.

Yan RT, Yan AT, Allegrone J, Lopez-Sendon J, Granger C, Gore J, Budaj A, Georgescu A, Hassan Q, Goodman SG . Failure To Identify St-Segment Deviation Or Left Bundle Branch Block On The Presenting Electrocardiograms In Patients With Acute Coronary Syndromes Is Related To More Adverse Clinical Outcome. Can J Cardiol 2006; 22(Suppl D):194D.

RT Yan RT, Yan AT, Allegrone J, Kennelly B, Budaj A, Georgescu A, Hassan Q, Goodman SG . ST-segment Depression in Non-ST Elevation Acute Coronary Syndromes: Quantitative Analysis Does Not Provide Incremental Prognostic Value Beyond Comprehensive Risk Stratification. Can J Cardiol 2006; 22(Suppl D):190D.

Yan AT, Yan RT, Tan M, Mendelsohn A, Jolly S, Fitchett D, Langer A, Goodman SG . Global Registry of Acute Coronary Events (Grace) Risk Score and Continuous ST-Segment Monitoring Provide Complementary Long-Term Prognostic Information in Patients with Non-St Elevation Acute Coronary Syndromes. Can J Cardiol 2006; 22(Suppl D):167D.

Fu Y, Goodman SG , Wagner G, Granger CB, Van de Werf F, Ross A, Armstrong PW. Q-Waves at Presentation Relate to Presentation Delay and Predict Reperfusion Likelihood and Subsequent Mortality. Can J Cardiol 2006;22(Suppl D):166D.

Bainey KR, Fu Y, Wagner G, Goodman SG , Ross A, Granger CG, Van de Werf F, Armstrong PW. Early ST Resolution in STEMI: Spontaneous Reperfusion in Acute Myocardial Infarction. Can J Cardiol 2006;22(Suppl D):165D.

Westerhout CM, Chang WC, Fu Y, Goodman SG , Van de Werf F, Granger CB, Armstrong. Are STEMI outcomes after fibrinolysis worse during "off hours"? Insights on circadian rhythm from ASSENT-2. Circulation 2005; 112(Suppl):II-320.

Toma M, Fu Y, Wagner G, Goodman SG , Van de Werf F, Granger CB, WallentinL, Armstrong PW, for the ASSENT 3 Investigators. Enriching The Prognostic Value Of The Baseline ECG In STEMI. Can J Cardiol 2005;21(Suppl C):247C.

PEER REVIEW PUBLICATIONS - ECG Core Laboratory | Abstracts (cont'd)

Toma M, Fu Y, Wagner G, Goodman SG , Van de Werf F, Granger CB, Wallentin L, Armstrong PW, for the ASSENT 3 Investigators. Risk Stratification In STEMI Is Enhanced By Using Both Baseline ST Deviation And ST Resolution At 180 mins. Can J Cardiol 2005;21(Suppl C):163C.

Westerhout CM , Chang WC, Fu Y, Goodman SG , Van de Werf F, Granger CB, Armstrong PW. Are STEMI Outcomes After Fibrinolysis Worse During "Off Hours"? Insights On Circadian Rhythm From ASSENT-2. Can J Cardiol 2005;21(Suppl C):90C.

Taher T, Al-Kurtass S, Fu Y, Wagner G, Goodman SG, Welsh R, Granger C, Wallentin L, Van de Werf F, Armstrong PW. The ECG Adds Value to Time to Treatment in Predicting Aborted Myocardial Infarction. JACC 2005;45(Suppl A):194A.

Yan AT, Goodman SG , Kennelly BM, Anderson FA, Allegrone J, Steg PG, on behalf of the GRACE Investigators. Prevalence and prognostic significance of ST elevation in aVR: Insights from the Global Registry of Acute Coronary Events Electrocardiographic Substudy. Eur Heart J 2005;26 (Abstr Suppl):282.

Alghamdi S, Fu Y, Goodman SG , Chang W-C, Van de Werf F, Granger CB, Armstrong PW. The Baseline ECG in ST Elevation Myocardial Infarction Provides Powerful Prognostic Insight: Observations from ASSENT 2. J Am Coll Cardiol 2005;45(Suppl A):208A.

Al-Kurtass S, Fu Y, Wagner G, Goodman S , Granger CB, Wallentin L, Van de Werf F, Armstrong PW. Does The Baseline ECG Add Value To Time To Treatment In Predicting Successful Reperfusion After Fibrinolysis?: Insight From ASSENT-3 And ASSENT 3+. Can J Cardiol 2004;20(Suppl D):108D.

Alexander J, Yang H, Becker RC, Kodama K, Dyke CK, Goodman SG , Kleiman NS, Hochman JS, Berger PB, Cohen EA, Lincoff M, Bovill EG, Kawai C, Armstrong PW, Harrington RA. Direct, selective factor Xa inhibition in patients with Non-ST elevation acute coronary syndromes from the United States, Canada, and Japan: results of the XaNADU-ACS Trial. J Am Coll Cardiol 2004;43(5;Suppl A):302A.

Yan AT, Yan R, Tan M, Fitchett DH, Cohen M, Armstrong PW, Langer A, Goodman SG . Early continuous ST monitoring identifies acute coronary syndrome patients at high risk of death and myocardial infarction despite contemporary treatment. J Am Coll Cardiol 2004;43(5;Suppl A):277A.

de Villiers JF, Fu Y, Wagner G, Goodman SG , Granger C, Wallentin L, Van de Werf F, Armstrong PW, for the ASSENT 3 Investigators. The acuteness score: new insights in predicting infarct size. J Am Coll Cardiol 2004;43(5;Suppl A):288A.

PEER REVIEW PUBLICATIONS - ECG Core Laboratory | Abstracts (cont'd)

Johanson P, Fu Y, Dellborg M, Goodman SG , Armstrong PW, Krucoff MW, Wallentin L, Wagner GS. The model for a continuously updated weather-forecast before, during and after reperfusion therapy for estimations of final myocardial salvage: an ASSENT-2 electrocardiogram/VCG substudy. Eur Heart J 2003;24 Abstr Suppl:722.

Taher T, Fu Y, Wagner G, Goodman SG , Fresco C, Granger CB, Wallentin L, Van de Werf F, Armstrong PW, University of Alberta for the ASSENT 3 Investigators. Evidence for early reperfusion and preservation of myocardium: a new salvage subset. J Am Coll Cardiol 2003;41(suppl A):358A

Al-Faleh H, Fu Y, Wagner GS, Goodman SG , Sgarbossa E, Granger CB, Van der Werf F, Wallentin L, Armstrong PW, for the ASSENT 3 Investigators. Unraveling the spectrum of LBBB in AMI: Insights from ASSENT 3. J Am Coll Cardiol 2003;41(suppl A):366A ).

Leung R, Fu Y, Goodman SG, Wagner G, Granger CB, Wallentin L, Van de Werf F, Armstrong PW, for the ASSENT 3 investigators. Does open-label reperfusion therapy in ST-elevation acute myocardial infarction influence the frequency of urgent percutaneous coronary intervention? Can J Cardiol 2002;18(suppl B):140B.

Taher T, Fu Y, Wagner G, Goodman SG , Fresco C, Granger CB, Wallentin L, Van de Werf F, Armstrong PW for the ASSENT 3 Investigators. Evidence for early reperfusion and preservation of myocardium: the ECG characteristics of aborted MI. Can J Cardiol 2002;18(suppl B):241B.

Wagner G, Fu Y, Goodman SG , Granger CB, Wallentin L, Van de Werf F, Armstrong P, on behalf of the ASSENT III investigators. How does ST-segment resolution one-hour after fibrinolysis for acute myocardial infarction predict final infarct size? Insights from ASSENT 3. Eur Heart J 2002;23(Abstr Suppl):266.

Armstrong PW, Wagner GS, Goodman S , Van de Werf F, Granger CB, Fu Y. Impact of fibrinolytic regimens and elapsed time on resolution of ST elevation in acute MI: insights from the ASSENT 3 ECG substudy. J Am Coll Cardiol 2002;39(suppl B):95B.

Lockwood E, Fu Y, Wong B, Goodman S , Van de Werf F, Granger C, Armstrong PW, for the ASSENT-2 Investigators. Does 24-hour ST segment resolution post-fibrinolysis add prognostic value to a Q-wave? ASSENT-2 electrocardiographic sub-study. Can J Cardiol 2001;17(suppl C):182C-183C.

Fu Y, Goodman S , Van de Werf F, Granger C, Armstrong P. The nature and outcome of patients who avoid myocardial necrosis after fibrinolysis. Eur Heart J 2001;22(Suppl):179.

PEER REVIEW PUBLICATIONS - ECG Core Laboratory | Abstracts (cont'd)

Fu Y, Goodman S, Chang W-C, Kaul P, Van de Werf F, Granger CB, Armstrong PW, for the ASSENT 2 Investigators. Time to treatment influences the impact of ST segment resolution on one year prognosis: insights from ASSENT-2. J Am Coll Cardiol 2001;37(suppl A):340A.

Fu Y, Goodman S, Chang W-C, Barr A, Lagos M, Jagasia P, Van de Werf F, Granger C, Armstrong PW, for the ASSENT II Investigators. Incidence and prognosis of non-Q wave MI in the thrombolytic era: insights from ASSENT II. J Am Coll Cardiol 2000;35(suppl.A):390A.

Sgarbossa EB, Pinskey SL, Pavlovic-Surjancev B, Barbagelata A, Goodman SG , Underwood DA, Lum AS, Palvas B, Allen JE, Starr S, Paredes A, Wagner GS. A new hierarchy for ECG stratification of acute myocardial infarction based in T wave polarity. Circulation 1998;98(suppl.I):I-555.

Sgarbossa EB, Pinski SL, Underwood DA, Stein S, Gates KB, Goodman S, Wager GS. Post-thrombolysis reversion of bundle branch block in acute myocardial infarction is associated with improved prognosis. Electrocardiology 1996;29:545-546.

Pinski SL, Steinberg JS, Goodman SG , Helguera ME, Connors, S, Song Q, Lawson WT, Gates K, Wagner GS. Lack of agreement in QT dispersion measurement by 3 different methods. PACE 1996; 19(4, Part II): 667.

Goodman SG , Langer A, Wildermann N, Barbagelata A, Sgarbossa EB, Wagner GS, Granger CB, Ross AM, Armstrong PW, for the GUSTO Investigators. Non-Q wave vs. Q wave MI following thrombolysis: angiographic insights. Circulation 1995;92(suppl.):I-530.

Goodman SG, Langer A, Wildermann N, Barbagelata A, Sgarbossa EB, Wagner GS, Granger CB, Califf RM, Ross AM, Armstrong PW, for the GUSTO Investigators. Non-Q wave vs. Q wave MI following thrombolysis: angiographic insights. Can J Cardiol 1995; 11 (suppl. E):110E.

Goodman SG , Langer A, Topol E, Armstrong PW. What is the natural history of non-Q infarction in the post thrombolytic era? Can J Cardiol 1993; 9(suppl.E):106E.

Goodman SG , Langer A, Freeman MR, Sutherland W, Armstrong PW. Ambulatory silent ischemia adds diagnostic value to exercise testing and thallium scintigraphy in stable angina. Can J Cardiol 1992; 8(suppl.B):81B.

Goodman SG, Langer A, Freeman MR, Sutherland W, Armstrong PW. Ambulatory silent ischemia adds diagnostic value to exercise testing and thallium scintigraphy in stable angina. Circulation 1992; 86(suppl. 4):I-185.

PEER REVIEW PUBLICATIONS - ECG Core Laboratory | Abstracts (cont'd)

Goodman SG , Langer A, Sutherland W, Adams L, Armstrong PW. Does ambulatory silent myocardial ischemia identify patients with more significant coronary artery disease? Can J Cardiol 1991; 7(suppl. A):105A.

ESSENCE

PEER REVIEW PUBLICATIONS | Manuscripts

Murphy SA, Antman E, Van de Werf F, Goodman SG , Mahaffey K, Menown I, Cohen M, Gibson CM. Efficacy and Safety of the Low-Molecular Weight Heparin Enoxaparin Compared with Unfractionated Heparin across the Acute Coronary Syndrome Spectrum: A Meta-Analysis. Eur Heart J 2007;28:2077-86.

Jolly S, Tan M, Mendelsohn A, Fitchett D, Armstrong PW, Langer A, Goodman SG , Comparison of Effectiveness of Enoxaparin versus Unfractionated Heparin to Reduce Silent and Clinically Apparent Acute Myocardial Infarction in patients presenting with non-ST Segment Elevation Acute Coronary Syndrome. Am J Cardiol 2007;99:186-188.

Spinler SA, Inverso SM, Cohen M, Goodman SG , Stringer KA, Antman EM, for the ESSENCE and TIMI 11B investigators. Safety and efficacy of unfractionated heparin versus enoxaparin in patients who are obese and patients with severe renal impairment: analysis from the ESSENCE and TIMI 11B studies. Am Heart J 2003;146:33-41.

Antman EM, Cohen M, McCabe C, Goodman SG, Murphy SA, Braunwald E. Enoxaparin is superior to unfractionated heparin for preventing clinical events at one year follow-up of TIMI 11B and ESSENCE. Eur Heart J 2002;23:308-14.

Goodman SG, Barr A, Sobtchouk A, Cohen M, Fromell GJ, Laperrière L, Hill C, Langer A, for the Canadian Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events (ESSENCE) ST Segment Monitoring Substudy Group. Low molecular weight heparin decreases rebound ischemia in unstable angina or non-Q wave myocardial infarction: The Canadian ESSENCE ST segment monitoring substudy. J Am Coll Cardiol 2000;36:1507-1513.

Goodman SG , Cohen M, Bigonzi F, Gurfinkel EP, Radley DR, Le Louer V, Fromell GJ, Demers C, Turpie AGG, Califf RM, Fox KAA, Langer A, for the Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group. Randomized trial of low molecular weight heparin (enoxaparin) versus unfractionated heparin for unstable coronary artery disease: one year results of the ESSENCE study. J Am Coll Cardiol, 2000;36:693-98.

PEER REVIEW PUBLICATIONS | Manuscripts (cont'd)

Cohen M, Stinnett S, Weatherly B, Gurfinkel EP, Fromell GJ, Goodman SG, Califf RM, Fox KAA, Lee KL, for the ESSENCE Study Group. Predictors of recurrent ischemic events and death in unstable coronary artery disease after treatment with combination antithrombotic therapy. Am Heart J 2000;139:962-70.

O'Brien BJ, Willan A, Blackhouse G, Goeree R, Cohen M, Goodman S . Is the use of low- molecular-weight heparin (enoxaparin) in acute coronary syndrome patients cost saving in Canada? Am Heart J 2000;139:423-29.

Fox KAA, Goodman S, Bigonzi F, Le Louer V, Cohen M, and the ESSENCE Trial Investigators. Inter-regional differences and outcome in unstable angina: analysis of the international ESSENCE trial. Eur Heart J 2000;21:1433-39.

Cohen M, Demers C, Gurfinkel EP, Turpie AGG, Fromell GJ, Goodman S , Langer A, Califf RM, Fox KAA, Premmereur J, Bigonzi F, for the Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q Wave Coronary Events Study Group. A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. N Eng J Med 1997;337:447-452.

Abstracts

Goodman SG , Bozovich G, Tan M, Dos Santos A, Hassan Q, Naebkhil A, Cohen M, Langer A, Bigonzi F, The ESSENCE Study Group. The greatest benefit of enoxaparin (low molecular weight heparin) over unfractionated heparin in acute coronary syndromes is achieved in patients presenting with ST segment depression. Circulation 2001;104(suppl.II):II-549.

Batchelor WB, Radley D, Cohen M, Turpie AGG, Langer A, Goodman S. A comparison of the impact of practice patterns on the outcomes of patients with acute coronary syndromes in the USA and Canada: post hoc analysis of ESSENCE and TIMI 11B. J Am Coll Cardiol 2001;37(suppl A):359A.

Goodman S, Langer A, Demers C, Turpie A, Bigonzi F, Radley D, Le louer V, Gosset F, Fromell G, Cohen M, for the ESSENCE Group. One year follow-up of the ESSENCE Trial (Enoxaparin vs. heparin in unstable angina/non Q wave myocardial infarction):sustained clinical benefit. Can J Cardiol 1998;14(suppl. F):122F.

Goodman S, Omarali I, Sobtchouk A, Barr A, Langer A, Cohen M, for the Canadian ESSENCE Holter Substudy Group. Low molecular weight heparin decreases rebound ischemia in unstable angina/non Q wave MI: the Canadian

ESSENCE Holter substudy. Can J Cardiol 1998;14(suppl. F):122F.

PEER REVIEW PUBLICATIONS | Abstracts (cont'd)

Goodman S, Bigonzi F, Radley D, Le louer V, Gosset F, Cohen M, for the ESSENCE Group. One year follow-up of the ESSENCE Trial (Enoxaparin versus heparin in unstable angina and non-Q-wave myocardial infarction). Eur Heart J 1998;19:50.

PEER REVIEW PUBLICATIONS - ESSENCE Study | Abstracts (cont'd)

Cohen M, Bigonzi F, Le louer V, Gosset F, Fromell GJ, Goodman S , for the ESSENCE Group. One year follow-up of the ESSENCE Trial (Enoxaparin versus heparin in unstable angina and non-Q-wave myocardial infarction) . J Am Coll Cardiol 1998;31(suppl. A):79A.

Cohen M, Turpie AGG, Demers C, Gurfinkel E, Fromell G, Langer A, Goodman S , Califf R, Fox K, Premmereur J, Bigonzi F, for the ESSENCE Group. Blind comparison of enoxaparin (a low molecular weight heparin) with standard heparin in the treatment of unstable coronary artery disease "the ESSENCE trial". Thromb Haemost 1997;77(suppl.):374.

Cohen M, Weatherley B, Lee KL, Gurfinkel EP, Fromell G, Goodman S , Fox KAA. Multivariable analysis of predictors of recurrent ischemic events and death in unstable angina and non-Q wave infarction after treatment with combination antithrombotic therapy: results from the ESSENCE trial. Circulation 1997;96(suppl.):I-596.

Omarali I, Sobtchouk A, Barr A, Goodman S , Cohen M, Langer A. Low molecular weight heparin decreases ischemia and ischemic rebound in acute coronary syndromes: ESSENCE substudy. Circulation 1997;96(suppl.):I-597.

GRACE

PEER REVIEW PUBLICATIONS - GRACE Registry | Manuscripts

Eagle KA, Nallamothu BK, Mehta RH, Granger CB, Steg PG, Van de Werf F, López-Sendón J, Goodman SG , Quill A, Fox KAA, for the Global Registry of Acute Coronary Events (GRACE) Investigators. Trends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we're getting better but we've got a long way to go. Eur Heart J 2008;29(5):609-17.

Spencer FA, Goldberg RJ, Gore JM, Fox KAA, Avezum A, Agnelli G, Kritharides L, Anderson FA, Goodman SG, FitzGerald G, Allegrone J, Brieger D, GRACE Investigators. Comparison of Utilization of Statin Therapy at Hospital Discharge and Six-Month Outcomes in Patients With an Acute Coronary Syndrome and Serum Low-Density Lipoprotein >=100 mg/dl Versus <100 mg/dl. Am J Cardiol 2007;100:913-918

Spencer FA, Goldberg RJ, Gore JM, Fox KAA, Avezum A, Agnelli G, Kritharides L, Anderson FA, Goodman SG , FitzGerald G, Allegrone J, Brieger D, for the GRACE Investigators. Comparison of Utilization of Statin Therapy at Hospital Discharge and 6-month Outcomes in Patients with an Acute Coronary Syndrome and Serum Low Density Lipoprotein =100 mg/dl versus < 100 mg/dl. Am J Cardiol 2007;100:913-18.

Nguyen MC, Lim YL, Walton A, Lefkovits J, Agnelli G, Goodman SG , Budaj A, Gulba DC, Allegrone J, Brieger D, for the GRACE Investigators. Combining warfarin and antiplatelet therapy after coronary stenting in the Global Registry of Acute Coronary Events: is it safe and effective to use just one antiplatelet agent? Eur Heart J 2007; 28(14):1717-22.

Goldberg RJ, Spencer FA, Steg PG, Flather M, Gurfinkel EP, Kennelly BM, Goodman SG , Dedrick R, Gore JM, for the GRACE Investigators. Increasing use of single and combination medical therapy in patients hospitalized for acute myocardial infarction in the 21st century: a multinational perspective. Arch Int Med 2007;167(16):1766-73.

Fox KAA, Steg PG, Eagle KA, Goodman SG , Anderson FA, Granger CB, Flather MD, Budaj A, Quill A, Gore JM, for the GRACE Investigators. Decline in Rates of Death and Heart Failure in Acute Coronary Syndromes. Temporal Trends - 1999 to 2006. Global Registry of Acute Coronary Events. JAMA 2007;297:1892-1900.

PEER REVIEW PUBLICATIONS - GRACE Registry | Manuscripts (cont'd)

Yan A, Yan R, Kennelly B, Anderson F, Budaj A, Lopez-Sendon J, Brieger D, Allegrone J, Steg PG, Goodman SG . Relationship of ST Elevation in Lead aVR with Angiographic Findings and Outcome in Non-ST Elevation Acute Coronary Syndromes. Am Heart J 2007;154:71-8.

Goldberg RJ, Spencer FA, Steg PG, Flather M, Gurfinkel EP, Kennelly BM, Goodman SG , Dedrick R, Gore JM, for the GRACE Investigators. Increasing Use of Combination Medical Therapy in Patients Hospitalized for Acute Myocardial Infarction in the 21 st Century: A Multinational Perspective. Arch Int Med 2007; 167(16):1766-73.

Steg PG, Lopez-Sendon J, Lopez de Sa E, Goodman SG , Gore JM, Anderson FA, Himbert D, Allegrone J, Van de Werf F. External Validity of Clinical Trials in Acute Myocardial Infarction. Arch Int Med 2007;167:68-73.

Brieger D, Van de Werf F, Avezum A, Montalescot G, Kennelly BM, Granger CB, Goodman SG , Dabbous OH, Agnelli G, for the GRACE Investigators. Interactions Between Heparins, Glycoprotein IIb/IIIa Antagonists, and Coronary Intervention. The Global Registry of Acute Coronary Events. American Heart Journal 2007;153:960-69.

Fox KAA, Dabbous OH, Goldberg RJ, Pieper KS, Eagle KA, Van de Werf F, Avezum A, Goodman SG , Flather MD, Anderson Jr FA, Granger CB, for the GRACE Investigators. Prediction of the risk of death and myocardial infarction in the six months following presentation with ACS: a prospective, multinational, observational study (GRACE). British Medical Journal 2006;333:1091-94.

Fox KAA, Anderson Jr FA, Dabbous OH, Steg PG, López-Sendón J, Van de Werf F, Budaj A, Gurfinkel EP, Goodman SG , Brieger D, on behalf of the GRACE Investigators. Intervention in acute coronary syndromes: do patients undergo intervention on the basis of their risk characteristics? The Global Registry of Acute Coronary Events (GRACE). Heart 2007;93(2):177-82.

Goodman SG , Steg PG, Eagle KA, Fox KAA, Lopez-Sendon J, Montalescot G, Budaj A, Kennelly BM, Gore JM, Allegrone J, Granger CB, Gurfinkel EP. The diagnostic and prognostic impact of the redefinition of acute myocardial infarction: Lessons from the Global Registry of Acute Coronary Events (GRACE). Am Heart J 2006;151:654-660.

PEER REVIEW PUBLICATIONS - GRACE Registry | Manuscripts (cont'd)

Van de Werf F, Gore JM, Avezum A, Gulba DC, Goodman SG , Budaj A, Brieger D, White K, Fox KAA, Eagle KA, Kennelly BM, for the GRACE Investigators. Access to catheterisation facilities in patients admitted with acute coronary syndrome: multinational registry study. British Medical Journal 2005;330:441.

Eagle KA, Lim MJ, Dabbous OH, Pieper KS, Goldberg RJ, Van de Werf F, Goodman SG , Granger CB, Steg PG, Gore JM, Budaj A, Avezum A, Flather MD, Fox KAA, for the GRACE Investigators. A validated prediction model for all forms of acute coronary syndromes: estimating the risk of six-month post-discharge death in the global registry of acute coronary events (GRACE). JAMA 2004;291:2727-33.

Brieger D, Eagle KA, Goodman SG , Steg PG, Budaj A, White K, Montalescot G, for the GRACE Investigators. Acute coronary syndromes without chest pain: an underdiagnosed and undertreated high-risk group. Insights from the Global Registry of Acute Coronary Events (GRACE). Chest 2004;126:461-469.

Eagle KA, Kline-Rogers E, Goodman SG, Gurfinkel EP, Avezum A, Flather MD, Granger CG, Erickson S, White K, Steg PG. Adherence to Evidence-Based Therapies After Discharge for Acute Coronary Syndromes. An Ongoing, Prospective, Observational Study. Am J Med 2004;117:73-81.

Budaj A, Brieger D, Steg PG, Goodman SG , Fox KAA, Avezum A, Cannon CP, Mazurek T, Flather M, Dabbous OH, Van de Werf F, for the GRACE Investigators. Global patterns of use of antithrombotic and antiplatelet therapy in patients with acute coronary events. Insights from the Global Registry of Acute Coronary Events (GRACE). Am Heart J 2004;146:999-1006.

Goldberg RJ, Currie K, Sadiq I, Brieger D, Steg PG, Goodman SG , Gore JM. Six-month outcomes in a multinational registry of patients hospitalized with an acute coronary syndrome (The Global Registry of Acute Coronary Events [GRACE]). Am J Cardiol 2004;93:288-93.

Furman MI, Gore JM, Anderson FA, Budaj A, Goodman SG , Avezum A, López-Sendón J, Klein W, Mukherjee D, Eagle K, Dabbous OH, Goldberg RJ, for the GRACE Investigators. Elevated Leukocyte Count and Adverse Hospital Events in Patients with Acute Coronary Syndromes: Findings from the Global Registry of Acute Coronary Events (GRACE). Am Heart J 2004;147:42-8.

Fox KAA, Goodman SG , Anderson FA, Granger CB, Moscucci M, Flather MD, Spencer F, Budaj A, Dabbous OH, Gore JM, on behalf of the GRACE Investigators. From guidelines to clinical practice: the impact of hospital and geographical characteristics on temporal trends in the management of acute coronary syndromes. The Global Registry of Acute Coronary Events (GRACE). Eur Heart J 2003;24:1414-24.

PEER REVIEW PUBLICATIONS - GRACE Registry | Manuscripts (cont'd)

Granger CB, Goldberg RJ, Dabbous O, Pieper KS, Eagle KA, Cannon CP, Van de Werf F, Avezum A, Goodman SG , Flather MD, Fox KAA, for the GRACE investigators. Predictors of hospital mortality in the Global Registry of Acute Coronary Events. Arch Intern Med 2003;163:2345-2353.

Fox KAA, Goodman SG , Klein W, Brieger D, Steg PG, Dabbous O, Avezum A. Management of acute coronary syndromes. Variations in practice and outcome: findings from the Global Registry of Acute Coronary Events (GRACE). Eur Heart J 2002;23:1177-1189.

Goldberg RJ, Steg PG, Granger CB, Jackson EA, Budaj A, Brieger D, Avezum A, Goodman SG. Extent of, and factors associated with, delay to hospital presentation in patients with acute coronary disease (The GRACE Registry). Am J Cardiol 2002;89(7):791-6.

Eagle KA, Goodman SG , Avezum A, Budaj A, Sullivan CM, Lopez-Sendon J, for the GRACE investigators. Practice variation and missed opportunities for reperfusion in ST-segment elevation myocardial infarction: findings from the Global Registry of Acute Coronary Events (GRACE). Lancet 2002;359:373-77.

The GRACE Investigators. GRACE (Global Registry of Acute Coronary Events) project: A multinational registry of patients hospitalized with acute coronary syndromes. Am Heart J 2001;141:190-199.

Abstracts

Gore JM, Marre M, Steg PG, Brieger D, Quill A, Goodman SG , for the GRACE Investigators. Treatment and Outcome of Diabetic Patients with an Acute Coronary Syndrome: Has There Been any Improvement Over Time? The GRACE Registry. J Am Coll Cardiol 2008;51(Suppl A):A244.

LaBounty T, Gurm HS, Goodman SG , Montalescot G, Lopez-Sendon J, Quill A, Eagle KA. Predictors and Implications of Q-waves in ST-Elevation Myocardial Infarction: A Contemporary Perspective from the Global Registry of Acute Coronary Events. Circulation 2007;116(Suppl 2):11-526.

Yan AT, Yan RT, Welsh RC, Wong GC, Lornder JM, Rose B, Goodman SG. Validation of the Multinational, Registry-Derived GRACE Risk Score in a Broad Spectrum of Acute Coronary Syndrome Patients in Canada. Can J Cardiol 2007;23(Suppl C):98C.

PEER REVIEW PUBLICATIONS - GRACE Registry | Abstracts (cont'd)

Yan RT, Yan AT, Welsh RC, Wong GC, Kornder JM, Rose B, Goodman SG. Coronary Angiography and Revascularization are Paradoxically Directed Towards Lower Risk Non-ST Elevation Acute Coronary Syndrome Patients: Contemporary Insights from from GRACE & GRACE 2 in Canada. Can J Cardiol 2007;23(Suppl C):121C.

Wang T, Goodman SG , Flather MD, Gurfinkel EP, Quill AL, Menon V. No impact of drug-eluting stents on rates of in-hospital coronary artery bypass surgery following non-ST-segment elevation myocardial infarction. The GRACE registry. Eur Heart J 2007;28(Suppl 1):735.

Gore J, Fox KA , Eagle KA, Furman M, Van De Werf F, Montalescot G, Goodman SG, Avezum A, Huang W, PG. Steg PG. Increased all-cause mortality at 2 year follow-up after PCI with drug-eluting stents vs bare metal stents in acute coronary syndromes: the Global Registry of Acute Coronary Events experience. Eur Heart J 2007 (in press).

Devlin G, Swanson N, Silverstone A, Montalescot G, Eagle KA, Goodman SG , Huang W, Brieger D. Do treatment delays influence outcomes following presentation with non-ST elevation acute coronary syndrome? The GRACE Registry. Eur Heart J 2007;28(Suppl 1):65.

Jolly S, Goodman SG , Shenkman H, Brieger D, Fox KA, Yan AT, Anderson FA, Allegrone J, Eagle KA. Quantitative Troponin Predicts Cardiogenic Shock, Sustained Ventricular Arrhythmias, Cardiac Arrest and Reinfarction in Non-ST Elevation Acute Coronary Syndromes. The GRACE Registry. Can J Cardiol 2006;22(Suppl D).166D.

Jolly S, Goodman SG, Shenkman H, Brieger D, Fox KA, Yan AT, Anderson FA,
Allegrone J, Eagle KA. Quantitative Troponin Predicts Cardiogenic Shock,
Sustained Ventricular Arrhythmias, Cardiac Arrest and Reinfarction in
Non-St Elevation Acute Coronary Syndromes. The Grace Registry. Eur
Heart J 2006;27(Suppl):1447.

PEER REVIEW PUBLICATIONS - GRACE Registry | Abstracts (cont'd)

Lopez-Sendon JL, Goodman SG , Steg PG, Brieger D, Eagle K, Granger C, Gurfinkel E, Dedrick R, Gore JM, for the GRACE Investigators. Heparin Therapy During Fibrinolysis in ST-Segment Elevation Myocardial Infarction: Registry Data Support Clinical Trial Results. Circulation 2006;114(Suppl):II-863.

Nguyen M, Lim YL, Walton A, Lefkovits J, Agnelli G, Goodman SG , Budaj A, Gulba DC, Allegrone J, Brieger D, for the GRACE Investigators. Combining warfarin and antiplatelet therapy after coronary stenting in the Global Registry of Acute Coronary Events: is it safe and effective to use just one antiplatelet agent? J Am Coll Cardiol 2006;47(Suppl A):252A.

Eagle KA, Mehta RH, Nallamothu BK, Granger CB, Steg PG, Van de Werf F, Lopez-Sendon J, Goodman SG , Allegrone J, Fox KA, for the GRACE Investigators. Global reperfusion therapy in acute myocardial infarction - 1999 to 2004: We're getting better, but we have a long way to go. The Global Registry of Acute Coronary Events. Circulation 2005; 112(Suppl):II-794.

Petersen JL, Reist CJ, Col JJ, Anderson FA, Fox KAA, Goodman SG , Langer A, Ferguson JJ. Patient characteristics and clinical events from GRACE and SYNERGY: differences persist in utilization of standard therapies in clinical practice. Circulation 2005; 112(Suppl):II-776

Fox KA, Anderson FA, Goodman SG , Dabbous OH, Gore JM, on behalf of the GRACE Investigators. Time course of events following presentation with acute coronary syndrome: observations from 33,402 patients in the Global Registry of Acute Coronary Events. Eur Heart J 2005;26 (Abstr Suppl):118.

Goodman SG , Yan AT, Allegrone J, Lopez-Sendon J, Granger CB, Gore JM, Budaj A, Georgescu AA, Hassan Q, Luchansky J, Van de Werf F, for the GRACE ECG Substudy Investigators. Disagreement in the Interpretation of the Admission Electrocardiogram in Acute Coronary Syndromes and Association With Clinical Outcome: Real-World Insights From GRACE. JACC 2005;45(Suppl A):240A.

Spencer FA, Gore JM, Oliveira G, Montalescot G, Fox KAA, Goodman SG , Malone S, Granger CB, on behalf of the GRACE Investigators. Determinants of delay in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction. The Global Registry of acute coronary events. Eur Heart J 2005;26 (Abstr Suppl):621.

PEER REVIEW PUBLICATIONS - GRACE Registry | Abstracts (cont'd)

Steg PG, López-Sendón J, Lopez de Sa E, Goodman SG , Gore JM, Anderson FA Jr, Himbert D, Allegrone J, Van de Werf F, for the GRACE Investigators. Comparison of patients with ST-segment elevation myocardial infarction enrolled in fibrinolytic drug trials with trial-eligible and trial-ineligible patients. Findings from the Global Registry of Acute Coronary Events. Circulation 2004;110(Suppl III):III-783.

Jelinek M, Goodman SG , López-Sendón J, Gurfinkel E, White K, Brieger D. The impact of the new definition of acute myocardial infarction on patients discharged with unstable angina pectoris -- six month outcomes: the Global Registry of Acute Coronary Events (GRACE). Eur Heart J 2003;24 Abstr Suppl:723.

Fox KAA, Anderson F, Goodman SG , Budaj A, Granger C, Flather M, Spencer F, Moscucci M, Dabbous O, Gore JM. Influence of guidelines and results from major clinical trials on medical practice: findings from the Global Registry of Acute Coronary Events (GRACE). J Am Coll Cardiol 2003;41(suppl A):518A

Goodman S, Granger CB, White K, Brieger D, Budaj A, Dabbous OH, Steg PG, on behalf of the GRACE Investigators. Acute coronary syndrome patients with ST segment depression have substantial mortality rates but undergo less aggressive management strategies: insights from the Global Registry of Acute Coronary Events (GRACE). J Am Coll Cardiol 2003;41(suppl A):325A.

Eagle KA, Lim MJ, Budaj A, Dabbous OH, Pieper K, Goodman SG , Granger CB, Steg PG, Gore JM, Fox KA. A robust prediction model for all forms of acute coronary syndromes: estimating the risk of in-hospital death and myocardial infarction in the Global Registry of Acute Coronary Events (GRACE). J Am Coll Cardiol 2003;41(suppl A):353A.

Brieger D, Eagle KA, Goodman SG, Lopez-Sendon J, Steg PHG, Budaj A, White K, Montalescot G, on behalf of the GRACE investigators. Atypical presentation of acute coronary syndromes independently predicts myocardial infarction and increased in-hospital mortality: insights from the GRACE registry. Eur Heart J 2002;23(Abstr Suppl):105.

Steg PHG, Feldman LJ, Brami M, Vahanian A, Eagle KA, López-Sendón J, Dabbous O, Goodman SG , on behalf of the GRACE investigators. Recurrent ischaemia in acute coronary syndromes: differential impact of electrocardiographic changes on outcomes. Eur Heart J 2002;23(Abstr Suppl):588.

Fox KAA, Goldberg RJ, Pieper K, Cannon CP, Van de Werf F, Goodman SG , Dabbous O, Granger CB, on behalif of the GRACE investigators. Predictors of in-hospital mortality in the global registry of acute coronary events (GRACE). Eur Heart J 2002;23(Abstr Suppl):626.

PEER REVIEW PUBLICATIONS - GRACE Registry | Abstracts (cont'd)

Furman MI, Davidson MC, Anderson FA, Jr, Budaj A, Goodman SG , Avezum A, Lopez-Sendon J, Klein W, Gore JM. Relationship between elevated leukocyte count and hospital clinical events in patients with acute coronary syndromes: findings from the Global Registry of Acute Coronary Events. Circulation 2001;104(suppl II):II-650.

Gurfinkel EP, Duronto E, Lopez de Sa E, Avezum A, Sadiz I, Klein W, Goldberg RJ, Johnson J, Goodman SG. 'Necrosette' infarction versus traditionally defined non-ST-segment elevation myocardial infarction (NSTEMI) and in-hospital course. Findings from the Global Registry of Acute Coronary Events (GRACE). Eur Heart J 2001;22(Suppl):519.

Van de Werf F, Avezum A, Gulba D, Goodman S , Budaj A, Brieger D, Gore J, Cannon C, White K, Kennelly B. Interventional procedures and in-hospital outcomes in patients with acute coronary syndromes: observations from the Global Registry of Acute Coronary Events (GRACE). Eur Heart J 2001;22(Suppl):617.

Goodman S, Johnson J, Sullivan C, Steg Ph G, Eagle K, Fox KAA, Lopez-Sendon J, Montalescot G, Budaj A, Kennelly B, Gore J, for the GRACE Investigators. What is an MI? Prospective analysis of the diagnostic and prognostic impact of adding troponins to the definition of myocardial infarction. J Am Coll Cardiol 2001;37(suppl A):358A.

HIGH VASCULAR RISK QUERIS REGISTRIES

PEER REVIEW PUBLICATIONS | Manuscripts

Yan AT, Yan RT, Tan M, Hackam DG, Leblanc KL, Kertland H, Tsang JL, Jaffer S, Kates ML, Leiter LA, Fitchett DH, Langer A, Goodman SG , for the Vascular Protection (VP) and Guidelines Oriented Approach to Lipid Lowering (GOALL) Registries Investigators. Contemporary Management of Dyslipidemia in High-Risk Patients: Targets Still Not Met. Am J Med 2006 Aug;119(8):676-83.

Hackam DG, Tan MK, Lin PJ, Mehta PG, Jaffer S, Kates ML, Oh M, Grima EA, Langer A, Goodman SG. Vascular Protection Registry and Guideline Oriented Approach in Lipid Lowering Registry Investigators. Supporting a call to action for peripheral vascular disease: Insights from two prospective registries. J Vasc Surg 2006;44:776-81.

Hackam DB, Tan MKK, Honos GN, Leiter LA, Langer A, Goodman SG , for the Vascular Protection (VP) Registry Investigators. How does the prognosis of diabetes compare with that of established vascular disease? Insights from the Canadian Vascular Protection (VP) Registry. Am Heart J 2004;148:1028-33.

Abstracts

Yan AT, Yan RT, Saposnik G, Fitchett DH, Leiter L, Langer A, Goodman SG . Treatment of Dyslipidemia in Patients with Cerebrovascular Disease: the Canadian VP and GOALL Regristries Experience. J Am Coll Cardiol 2008;51(Suppl A):A238.

Saposnik G, Yan AT, Casanova A, Langer A, Goodman SG, for the Stroke Outcome Research Canada (SORCan) Working Group. Gender Differences In The Management Of Cerebrovascular Disease: The Challenge Of Secondary Prevention. Stroke 2008;(in press).

Gustavo Saposnik G, Yan AT, Yan RT, Fitchett D, Neville Bayer N, Leiter L, Langer A, Goodman SG, for the Guidelines Oriented Approach in Lipid Lowering (GOALL) Registry and Vascular Protection (VP) Registry. Differences In Target Achievement Among Patients With Cardiovascular, Stroke Or Combined Disease

Stroke 2008;(in press).

Langer A, Bissonnette S, Goodman SG , Tan M, Casanova A, Leiter LA. Dyslipidemia Management in Patients with Diabetes: The Guidelines Based Undertaking for Improvement in Dyslipidemia Related Events (GUIDE) Experience. Can J Cardiol 2007;23(Suppl C):196C.

Langer A, Goodman S , Dawson K, Fitchett D, Gerstein HC, Harris S, Honos G, McFarlane P, Steele A, Ur E, Yale JF, Leiter L. Ongoing Care Gap in Canadian Diabetes Management. Can J Cardiol 2006;22(Suppl D):83D.

Yan RT, Yan AT, Saposnik G, Fitchett DH, Leiter L, Langer A, Goodman SG. Treatment of Dyslipidemia in Patients with Cerebrovascular Disease: the Canadian VP and GOALL Registries Experience. Can J Cardiol 2007;23(Suppl C):99C.

Langer A, Grima DT, Leiter LA, Attard CL, Goodman SG . The Real Cost of Care Gap in Management High Cardiovascular Risk Patients: A Canadian Population Analysis. Can J Cardiol 2006;22(Suppl D):111D.

Yan RT, Yan AT, Tan M, Leiter LA, Fitchett D, Langer A, Goodman SG . High Vascular Risk Patients and Achievement of Guideline-Recommended LDL-Cholesterol Targets: Predictors of Treatment Failure. Can J Cardiol 2006; 22(Suppl D):84D.

Tsang JLY, Mendelsohn A, Tan M, Hackam DG, Leiter L, Fitchett D, Langer A, Goodman SG for the VP & GOALL Registry Investigators. The Use of Evidence-Based Cardioprotective Medications in High Vascular Risk Canadian Outpatients is Suboptimal. Circulation 2005;112(Suppl):II-445.

Yan RT, Yan AT, Tan M, Kertland HR, Leblanc KL, Leiter LA, Kates ML, Leong JC, Fitchett DH, Langer A, Goodman SG . Age-related Differences in the Lipid Profile and Use of Statin Therapy Among High Risk Patients: Targets Still Not Being Met. Can J Cardiol 2005;21(Suppl C):54C.

Yan AT, Yan RT, Tan M, Oh M, Kertland HR, Leblanc KL, Leiter LA, Chan J, Zavodni L, Langer A, Goodman SG , for the GOALL Registry Investigators. Canadian Patients at High Vascular Risk Received Suboptimal Doses of Statin Therapy With Only Half Achieving Guideline-Recommended Lipid Targets. Can J Cardiol 2005;20(Suppl D):181D.

Yan AT, Yan RT, Tan M, Oh M, Lonn E, Hackam DG, Chen RY, Booth G, Leiter LA, Langer A, Goodman SG , for the GOALL Registry investigators. Diabetic Patients Were Less Likely to be Treated with Guideline-Recommended Therapies, Can J Cardiol 2004;20(Suppl D):181D.

Yan RT, Yan AT, Tan M, Oh M, Leiter LA, Lonn E, Cheng AY, Langer A, Goodman SG , for the GOALL Registry Investigators. Obesity is an Independent Predictor and Therapeutic Target of Metabolic Abnormalities Among Treated High Vascular Risk Canadian Patients. Can J Cardiol 2004;20(Suppl D):183D.

INTERACT

PEER REVIEW PUBLICATIONS | Manuscripts

Yan AT, Yan RT, Huynh T, DeYoung P, Weeks A, Fitchett DH, Langer A, Goodman SG, for the INTERACT Investigators. Bleeding and Outcome in Acute Coronary Syndrome: Insights from Continuous ECG Monitoring in the INTERACT Trial. Am Heart J 2008; (in press).

Yan AT, Yan RT, Tan M, Senaratne M, Fitchett DH, Langer A, Goodman SG . Long-term Prognostic Value and Therapeutic Implications of Continuous ST-Segment Monitoring in Acute Coronary Syndromes. Am Heart J 2007;153:500-506.

Fitchett D, Langer A, Armstrong PW, Tan M, Mendelsohn A, Goodman SG . Randomized evaluation of the efficacy of enoxaparin versus unfractionated heparin in high risk patients with non-ST segment elevation acute coronary syndromes receiving the glycoprotein IIb/IIIa inhibitor eptifibatide. Long term results of the INTERACT trial. Am Heart J 2006;151:373-379.

Goodman SG . Enoxaparin and glycoprotein IIb/IIIa inhibition in non-ST-elevation acute coronary syndrome: Insights from the INTERACT trial. Am Heart J 2005;149(Suppl):S73-80.

Goodman SG, Fitchett D, Armstrong PW, Tan M, Langer A, for the Integrillin and Enoxaparin Randomized Assessment of Acute Coronary Syndrome Treatment (INTERACT) Trial Investigators. Randomized evaluation of the safety and efficacy of enoxaparin vs unfractionated heparin in high-risk pts with non-ST-segment elevation acute coronary syndromes receiving the glycoprotein IIb/IIIa inhibitor eptifibatide. Circulation 2003;107:238-244.

Abstracts

Yan AT, Yan RT, Tan M, Huynh T, Fitchett DH, Langer A, Goodman SG . Bleeding and Outcome in Acute Coronary Syndrome: Insights from Continuous ECG Monitoring in the INTERACT Trial. Circulation 2007;116(Suppl 2):11-481.

PEER REVIEW PUBLICATIONS - INTERACT Trial | Abstracts (cont'd)

Yan AT, Yan RT, Tan M, Huynh T, Fitchett DH, Langer A, Goodman SG. Bleeding and Outcome in Acute Coronary Syndrome: Insights from Continuous ECG Monitoring in the INTERACT Trial. Can J Cardiol 2007;23(Suppl C):223C.

Yan AT, Yan RT, Tan M, Mendelsohn A, Jolly S, Fitchett DH, Langer A, Goodman SG . Long-term Prognostic Value and Therapeutic Implications of Continuous ST-segment Monitoring in Acute coronary Syndrome. J Am Coll Cardiol 2007;49(Suppl A):204A.

Yan AT, Yan RT, Tan M, Armstrong PW, Granger CB, Dabbous O, Fox KA, Eagle KA, Huynh T, Fitchett DH, Langer A, Goodman SG. Enoxaparin is Consistently More Effective Than Unfractionated Heparin Across the Spectrum of Risk in Non-ST Elevation Acute Coronary Syndrome Patients: Insights from the INTERACT Trial. JACC 2005;45(Suppl A):230A.

SYNERGY

PEER REVIEW PUBLICATIONS | Manuscripts

Miller CD, Banerjee A, Mahaffey KW, Kontos M, Fermann G, Pollack CV, Antman EM, Aylward P, Goodman SG, Santos R, Ferguson JJ, Califf RM, Hoekstra JW. Treatment and Outcomes of Patients with Evolving Myocardial Infarction: Experiences from the SYNERGY Trial. Eur Heart J 2007;28(9):1079-84.

Cantor WJ, Mahaffey KW, Huang Z, Das P, Gulba DC, Glezer S, Gallo R, Ducas J, Cohen M, Antman EM, Langer A, Kleiman NS, White HD, Chisholm RJ, Harrington RA, Ferguson JJ, Califf RM, Goodman SG . Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal. Catheter Cardiovasc Interv 2007;69(1):73-83.

Mahaffey KW, Cohen M, Garg J, Antman E, Kleiman NS, Goodman SG, Berdan LG, Reist CJ, Langer A, White HD, Aylward P, Col JJ, Ferguson JJ, Califf RM, on behalf of the SYNERGY Trial Investigators. High-Risk Patients with Acute Coronary Syndromes treated with Low Molecular Weight or Unfractionated Heparin: Outcomes at 6 months and 1 year in the SYNERGY Trial. JAMA 2005;294:2594-2600.

The SYNERGY Trial Investigators. Enoxaparin vs unfractionated heparin in high-risk patients with non-ST segment elevation acute coronary syndromes managed with an intended early invasive strategy. Primary results of the SYNERGY randomized trial. JAMA 2004;292:45-54.

Petersen JL, Mahaffey KW, Becker RC, Goodman SG , Kleiman NS, Marian AJ, Stone GW, Lansky AJ, Lincoff AM, Hazen SL, Nessel CC, Toro-Figueroa L, Tate L, Reist CJ, Cohen M, Califf RM, Ferguson JJ. Coordinated series of studies to evaluate characteristics and mechanisms of acute coronary syndromes in high-risk patients randomly assigned to enoxaparin or unfractionated heparin: Design and rationale of the SYNERGY Library. Am Heart Journal 2004;148:269-276.

PEER REVIEW PUBLICATIONS - SYNERGY Trial | Manuscripts (cont'd)

Petersen JL, Mahaffey KW, Hasselblad V, Antman E, Cohen M, Goodman SG, Langer A, Blazing MA, Le-Moigne-Amrani A, DeLemos JA, Nessel CC, Harrington RA, Ferguson JJ, Braunwald E; Califf RM. Efficacy and Bleeding Complications Among Patients Randomized to Enoxaparin or Unfractionated Heparin for Antithrombin Therapy in Non-ST-Segment Elevation Acute Coronary Syndromes: A Systematic Overview. JAMA 2004;292:89-96.

Abstracts

Goodman SG , Mahaffey KW, Chiswell K, Cohen M, Kontos MC, Antman EM, Ferguson JJ, Califf RM, Becker R. Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST segment elevation acute coronary syndromes treated with unfractionated heparin. J Am Coll Cardiol 2007;49(Suppl A):186A.

Tricoci P, Mahaffey KW, O'Grady KG, Pieper KS, Newby LK, Harrington RA, Goodman SG , Gulba DC, Col J, White HD, Aylward PE, French JK, Kleiman NS, Fergusson JJ, Califf RM. Troponin elevation after percutaneous coronary intervention predicts major cardiac adverse outcomes in patients with non ST segment elevation acute coronary syndromes: results from the SYNERGY trial. J Am Coll Cardiol 2007;49(Suppl B):22B.

Linefsky JP, Mahaffey KW, Pieper KS, Lin A, Reist CJ, Antman E, Goodman SG , French JK, Roe MT, Harrington RA, Ferguson JJ, Califf RM. Differences between site-reported and core laboratory creatine kinase-MB values in an international clinical trial: results from the SYNERGY trial. Circulation 2006;114(suppl):II-417.

Shishehbor M, Lincoff AM, Lansky A, Mahaffey KW, Stone G, Yang H, Marian AJ, Ferguson JJ, Califf RM, Goodman SG , Kleiman NS, Topol E, Hazen SL, Becker RC. Lipid peroxidation products independently predict mortality in patients presenting with non-ST segment elevation acute coronary syndromes: a SYNERGY Library analysis. Circulation 2005; 112(Suppl):II-388.

Shishehbor M, Lincolff AM, Yang H, Mahaffey KW, Becker RC, Goodman SG, Lansky A, Marian AJ, Stone G, Kleiman NS, Ferguson JJ, Califf RM, Topol E, Hazen SL. Plasminogen activator inhibitor-1 activity predicts clinical outcome in patients presenting with non-ST-segment elevation acute coronary syndromes: a SYNERGY Library analysis. Circulation 2005; 112(Suppl):II-140.

PEER REVIEW PUBLICATIONS - SYNERGY Trial | Abstracts (cont'd)

Rao SV, Mahaffey KW, Antman E, Kleiman NS, Ferguson JJ, Califf RM, Becker RC, Goodman SG , Aylward PE. Predictors of Major Bleeding and Transfusion in SYNERGY: Effects of Pretreatment Variables and Treatment Assignment. JACC 2005;45(Suppl A):247A.

Ferguson JJ, Mahaffey KW, Huang Y, Armstrong PW, Levine G, Kleiman NS, Goodman SG , Cohen M, Antman E, Califf RM. Enoxaparin Versus Unfractionated Heparin: Consequences of Treatment Duration on Efficacy and Safety in SYNERGY. JACC 2005;45(Suppl A):247A.

Mahaffey KW, Levine G, Gallo R, Ducas J, Goodman SG , Lokhnygina Y, Traylor L, Antman E, White HD, Becker RC, Col JJ, Cohen M, Harrington RA, Ferguson JJ, Califf RM. Relationships Between Renal Function, Age, and Obesity and Outcomes in High-Risk Patients with Acute Coronary Syndromes: Results from SYNERGY. JACC 2005;45(Suppl A):214A.

Cohen M, Mahaffey KW, Berdan LG, Reist CJ, Traylor L, Langer A, Goodman SG , Antman E, Dietrich F, Califf RM, Ferguson JJ. Superiority of Enoxaparin Low-Molecular-Weight Heparin Over Unfractionated Heparin in Patients With No Prior Antithrombin Therapy or Maintained on Consistent Antithrombin Therapy: Results From SYNERGY. JACC 2005;45(Suppl A):202A.

Cantor WJ, Goodman SG , Gallup D, Mahaffey KW, Gulba DC, Cohen M, Antman EM, Langer A, Kleiman NS, White HD, Chisholm RJ, Harrington RA, Ferguson JJ, Califf RM. Major Access Site Bleeding in Acute Coronary Syndrome Patients Undergoing Early Invasive Management can be Reduced With Radial Access and Smaller Sheath Sizes. Observations from the SYNERGY Trial. JACC 2005;45(Suppl A):191A.

T-AMI PUBLICATIONS

PEER REVIEW PUBLICATIONS - TRANSFER AMI Study | Manuscripts

Cantor WJ , Fitchett D , Borgundvaag B , Heffernan M , Cohen EA , Morrison LJ , Langer A , Mehta S , Lazzam C , Schwartz B , Dzavik V , Goodman SG . Rationale and design of the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI). Am Heart J 2008;155:19-25.

Cantor WJ, Burstein J, Choi R, Heffernan M, Dzavik V, Lazzam C, Duic M, Fitchett D, Tan M, Wawrzyniak J, Kassam S, Dhingra S, Morrison LJ, Langer A, Goodman SG . Transfer for urgent percutaneous coronary intervention early after thrombolysis for ST-elevation myocardial infarction: The TRANSFER AMI pilot feasibility study. Can J Cardiol 2006;22:1121-1126.

Abstracts

Cantor WJ , Fitchett D , Borgundvaag B , Heffernan M , Cohen EA , Morrison LJ , Langer A , Mehta S , Lazzam C , Schwartz B , Dzavik V , Goodman SG . Rationale and design of the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI). Am Heart J 2008;155:19-25.

Morrison LJ, Cantor WJ, Choi R, Heffernan M, Dzavik V, Lazzam C, Duic M, Fitchett D, Wawrzyniak J, Kassam SA, Goodman SG , Langer A. Infarction in Ontario - results of the TRANSFER-AMI pilot study. Prehospital Emergency Care January 2005;9(1):141.

Cantor WJ, Choi R, Heffernan M, Dzavik V, Lazzam C, Duic M, Fitchett D, Wawrzyniak J, Kassam S, Morrison LJ, Goodman SG , Langer A. Feasibility of facilitated PCI for ST-elevation myocardial infarction in Ontario - results of the TRANSFER-AMI pilot study. Can J Cardiol 2004;20(Suppl D):152D.

MISC

PEER REVIEW PUBLICATIONS | Manuscripts

Cantor W, Kim H, Jolly S, Moe G, Mendelsohn A, Kleinfeld A, Fitchett D. B-Type Natriuretic Peptide and Serum Unbound Free Fatty Acid Levels after Contemporary Percutaneous Coronary Intervention. J Invasive Cardiol 2008;20:186-188.

Fitchett D, Goodman SG , Langer A. Ischemic Stroke: a Cardiovascular Risk Equivalent? Lesson Learned from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Can J Cardiol 2007;(in press).

Fitchett DH, Borgundvaag B, Cantor W, Cohen E, Dhingra S, Fremes S, Gupta M, Heffernan M, Kertland H, Husain M, Langer A, Letovsky E , Goodman SG , for the Renewal of Non STE ACS Algorithm Group. Non ST Segment Elevation Acute Coronary Syndromes: A Simplified Risk Oriented Algorithm. Can J Cardiol 2006;22:663-677.

Fitchett D, Leiter LA, Goodman SG , Langer A. Lower is better: Implications of the Treat to New Targets (TNT) Trial for Canadian Patients. Can J Cardiol 2006;22:835-839.

Kaul P, Newby LK, Fu Y, Mark DB, Goodman SG , Wagner GS, Harrington RA, Granger CB, Van de Werf F, Ohman EM, Armstrong, for the VIGOUR Group. Relation between baseline risk and treatment decisions in non-ST elevation acute coronary syndromes: an examination of international practice patterns. Heart 2005;91 876-881.

Fitchett DH, Leiter LA, Tardif JC, Goodman SG, Langer A. Are Canadian Guidelines for Cholesterol Lowering in High-Risk Patients Optimal ? Can J Cardiol 2005;21:85-90.

Fitchett D, Welsh R, Langer A, Goodman S . Enoxparain and percutaneous coronary intervention: a Canadian perspective. Can J Cardiol 2005;21(6):501-07.

Levine GN, Lincoff AM, Ferguson JJ, Mahaffey KW, Goodman SG , Cannon CP, Theroux P, Fox KAA. Utilization of catheterization and revascularization procedures in patients with non-ST segment elevation acute coronary syndrome over the last decade. Catheterization and Cardiovascular Interventions 2005;66:149-157.

Hackam DG, Goodman SG , Anand SS. Management of risk in peripheral artery disease: Recent therapeutic advances. Am Heart J 2005;150:35-40.

Fitchett DH, Leiter LA, Tardif JC, Goodman SG, Langer A. Are Canadian Guidelines for Cholesterol Lowering in High-Risk Patients Optimal ? Can J Cardiol 2005;21:85-90.

Young W, McShane J, O'Connor T, Rewa G, Goodman SG , Jaglal SB, Cash L, Coyte PC, O'Connor T. Registered Nurses' experiences with an evidence based home care pathway for myocardial infarction clients. Canadian Journal of Cardiovascular Nursing 2004;14:24-31.

PEER REVIEW PUBLICATIONS (cont'd) | Manuscripts (cont'd)

Cantor WJ, Goodman SG , Cannon CP, Murphy SA, Charlesworth A, Braunwald E, Langer A. Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST elevation acute coronary syndromes: Observations from the OPUS-TIMI 16 Trial. Am Heart J 2005;149:275-83.

Sprecher DL, Goodman S, Kannampuzha P, Pearce GL, Langer A. Skin tissue cholesterol (SkinTc) is related to angiographically-defined cardiovascular disease. Atherosclerosis 2003;171:255-8.

Fitchett D, Goodman SG , Gupta M, Langer A. Preventing thrombosis: update of first-line therapy in the management of non ST segment elevation acute coronary syndromes. Can J Cardiol 2002;18:1-12.

Lee DS, Goodman S, Dean DM, Lenis J, Ma P, Gervais PB, Langer A. Randomized comparison of T-type versus L-type calcium-channel blockade on exercise duration in stable angina: results of the Posicor Reduction of Ischemia During Exercise (PRIDE) trial. Am Heart J 2002;144:60-7.

Fitchett D, Goodman SG, Langer A. New advances in the management of acute coronary syndromes: 1. Matching treatment to risk. Can Med Assoc J 2001;164(9):1309-16.

Fitchett D, Goodman SG , Langer A on behalf of The University of Toronto Div of Cardiology/Greater Toronto Area Community Cardiologists. Guidelines for the early management of acute coronary syndromes: focus on antithrombotic and antiplatelet therapy. Can J Cardiol 2000;16:1423-1432.

Barr A, Goodman S, Langer A. Bootstrap methods for selection of variables and for investigation of model stability, and the application of these methods to Cox proportional hazards. 14 th International Workshop on Statistical Modelling; 1999:429-435.

PEER REVIEW PUBLICATIONS (cont'd) | Manuscripts (cont'd)

Langer A, Fisher M, Califf RM, Goodman SG , O'Connor CM, Harrington RA, Fuster V, for the CARS Investigators. Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States as compared to Canada. Can J Cardiol 1999;15(10):1095-1102

Goodman SG , Hill, C, Bata I, Fung A, Higginson, L, Lam J, Massel D, McCans J, Nasmith J, Stanton E, Thompson C, Warnica W, Langer A, for the the Prospective Reinfarction Outcomes in the Thrombolytic Era Cardizem CD Trial (PROTECT) Study Research Group. Design of a randomized, double-blind clinical trial of diltiazem vs. atenolol in secondary prophylaxis post non-Q wave myocardial infarction. Can J Cardiol, 1996;12:1183-1190.

Goodman SG , Langer A, Durica SS, Raskob GE, Comp PC, Gary RJ, Hall JH, Kelley RP, Hua TA, Lee RJ, Fuster V. Safety and Anticoagulation Effect of a Low-Dose Combination of Warfarin and Aspirin in Clinically Stable Coronary Artery Disease. Am J Cardiol 1994;74:657-661.

Abstracts

Fitchett DH, Casanova A, Goodman SG , Tan M, Kornilova O, Langer A. Safety and efficacy of extended delayed release diltiazem for improved blood pressure control in family practice. J Clin Hypertens 2007;9(5)(Suppl A):A34.

Singh KP, Roe MT, Peterson ED, Chen AY, Mahaffey KW, Goodman SG , Harrington RA, Ohman EM, Gibler B, Pollack CV. The safety of antithrombin therapy in non-ST-segment elevation acute coronary syndrome patients. Results from the CRUSADE initiative. J Am Coll Cardiol 2005;45(Suppl A):233A.

Goodman SG, Barr A, Granger C, Ohman M, Langer A, Armstrong P, Gibler B, Topol E. Secular trends in the management of acute myocardial infarction medication errors and outcomes with fixed double-bolus r-PA vs bolus + weight-adjusted infusion t-PA fibrinolysis: The GUSTO-III experience. J Am Coll Cardiol 2001;37(suppl A):351A.

Langer A, Cannon CP, Goodman SG, Charlesworth A, Hill C, McCabe C, Braunwald E. International differences in acute coronary syndrome outcomes are related to angiography rates. J Am Coll Cardiol 2000;35(suppl.A):375A.

Langer A, Goodman SG, Reilly TM, Mousa SA, Racanelli AL, O'Connor C, O'Neill WW, Kleiman NS, Gurbel P, Daly RN. Second generation oral IIb/IIIa receptor blockade: phase II experience with roxifiban. J Am Coll Cardiol 2000;35( suppl.A):308A

PEER REVIEW PUBLICATIONS - Miscellaneous Studies | Abstracts (cont'd)

Langer A, Barr A, Goodman S, Stewart D. Canadian Acute Myocardial Infarction database: safety and potential benefit of heart rate lowering calcium channel blockers. Drugs of Today 1999; 35(suppl.B):17-19.

H Ping Kong W, Barr A, Goodman S, Langer A. Culprit vessel remodeling and reocclusion post-MI: CARS angiographic substudy. Circulation 1998;98(suppl.I):I-146.

Stewart DJ, Langer A, Goodman S , Barr A, Davies RF, Dupuis R, Ferguson J, Gardner MJ, Savard P, Sussex BA, Talajic M. Are calcium channel blockers post myocardial infarction safe? The CAMI experience. Circulation 1997;96(suppl.):I-700.

Langer A, Califf RM, Goodman SG, Fisher MR, Fuster V. Does higher intervention rate post MI result in better outcome in US vs Canada? Circulation 1996;94(suppl.):I-28.

Freeman MR, Goodman SG, Hsia T, Sloninko J, Mironov D, Hill C, Langer A. Prediction of extent of coronary artery disease early post infarction. Circulation 1996;94(suppl.):I-240.

Freeman MR, Goodman SG, Hsia T, Sloninko J, Mironov D, Hill C, Langer A. Prediction of extent of coronary artery disease early post infarction. Can J Cardiol 1996;12(suppl.E):116E.

Goodman SG , Langer A, Durica S, Raskob G, Comp PC, Gray RJ, Hall JH, Kelley RP, Hua TA, Lee RJ, Fuster V, for the Coumadin Aspirin Reinfarction (CARS) Pilot Study Group. Safety and anticoagulation effect of a low-dose combination of coumadin and aspirin. Can J Cardiol 1994;10(suppl. C):109C.

Singh N, Mironov D, Goodman SG , Morgan CD, Langer A. Treatment of silent ischemia in unstable angina: a randomized comparison of Isoptin SR versus Metoprolol. Can J Cardiol 1994;10(suppl. C):130C.

Goodman SG , Langer A, Topol EJ, Charlesworth A, Skene AM, Wilcox RG, Armstrong PW, for the LATE Study Investigators. Late thrombolysis improves prognosis in patients with ST depression. Can J Cardiol 1994;10(suppl. C):108C.

Goodman SG , Langer A, Topol EJ, Charlesworth A, Skene AM, Wilcox RG, Armstrong PW, for the LATE Study Investigators. Does late thrombolysis improve prognosis in patients with ST depression? J Am Coll Cardiol 1994; 23(suppl.):147A.

PEER REVIEW PUBLICATIONS - Miscellaneous Studies | Abstracts (cont'd)

Langer A, Goodman SG , Comp PC, Raskob G, Durica S, Gray RJ, Kelley RP, Hua TA, Lee RJ, Fuster V, for the Coumadin Aspirin Reinfarction (CARS) Pilot Study Group. Safety and anticoagulation effect of a low-dose combination of coumadin and aspirin. Circulation 1993; 88(suppl.):I-493.